ALMA welcomes progress on Gavi replenishment, calls for continued commitment to close the gap and advance global health equity

Dar es Salaam, 26 June 2025 – The African Leaders Malaria Alliance welcomes the outcome of the Global Summit on Health & Prosperity through Immunisation held in Brussels, which has mobilised more than US$9 billion in support of Gavi, the Vaccine Alliance, for its 2026 to 2030 strategy. Co-hosted by the European Union and the Gates Foundation, the summit brought together a record number of donor pledges, demonstrating strong global solidarity in a difficult aid environment.

The replenishment marks critical progress toward Gavi’s overall target of US$11.9 billion and will support the immunisation of 500 million additional children and the prevention of up to 8 million deaths. In the face of rising costs and growing health needs, these resources will help protect children from preventable diseases and strengthen primary health care and pandemic preparedness across low- and middle-income countries.

This outcome reflects continued confidence in Gavi’s life-saving mission, which has helped vaccinate more than 1.1 billion children and prevent over 17 million deaths over the past two decades. It also acknowledges the reforms and efficiencies Gavi is undertaking, including new partnerships to improve delivery and equity. We welcome Gavi’s continued collaboration with African governments, regional institutions such as Africa CDC, and local partners to ensure immunisation programmes remain equitable, integrated, and responsive to national priorities. 

At the same time, the funding gap remains significant. Governments, funding agencies, and philanthropic partners must build on this momentum to close the remaining gap and ensure that no child is left behind. Shortfalls in funding risk limiting the number of lives that can be saved and the reach of essential services.

Across Africa, protecting child health remains a central priority, as healthy children are more likely to stay in school, complete their education, and contribute to economic and social development. Immunisation is a key part of that pathway, ensuring children survive, grow, and live to their full potential. Vaccinated children are better equipped to withstand infectious diseases, and for illnesses like malaria, which continues to be a leading killer of children under five in Africa, this resilience can make the difference between life and death.

A child whose immune system has been strengthened through routine immunisation stands a better chance of recovering even when infected. We have witnessed the recent introduction of the malaria vaccine in countries such as Ghana, Kenya, Malawi, Cameroon, and others as a major advancement in disease prevention. With support from Gavi and its partners, millions of children are now receiving protection against malaria. This first-generation vaccine, while reducing severe illness and deaths, lays the foundation for future vaccines with greater efficacy that will help us accelerate progress towards elimination. We appreciate the leadership shown by countries in rolling out the vaccine, and we recognise the sustained commitment of donors who have made this possible.

We also recognise the growing support form Gavi and partners, for local manufacturing through the African Vaccine Manufacturing Accelerator (AVMA), which is helping to build sustainable vaccine supply systems within the continent.

Looking ahead, the Global Fund replenishment will be another critical test of global solidarity. As the largest source of external malaria financing, accounting for over 60% in many high-burden countries, the Global Fund plays a central role in funding essential tools such as medicines, mosquito nets, health worker training, and community-led responses. With climate change driving malaria into new areas and programme costs continuing to rise, a fully replenished Global Fund is vital to protect progress, uphold equity, and advance the goal of zero malaria. This year’s target of US$18 billion offers a path to save 23 million lives across malaria, TB, and HIV while building stronger, more resilient health systems.

The work is not finished. We must keep going.